June 10, 2025 - Trends

Supplement Stacks Are Evolving

Protein, peptides, and pill fatigue.
Mixed supplements

Wellness trends are transforming supplement habits.

Bought in. Nearly 70% of Americans take supplements to support well-being, according to The Vitamin Shoppe’s latest trend report. Now, they’re demanding science-backed results.

Muscle up. 66% of people are trying to consume more protein. Prioritizing convenience, they’re reaching for on-the-go options — RTDs are up 20% and bars/snacks climbed 28%, while powdered mix-ins fell 12%.

Age well. 75% of Americans are concerned about aging, and 21% say they’re doing “everything possible” to fight it. As longevity goes mainstream, searches for NAD+ on The Vitamin Shoppe’s website are up 500%, fueling a 91% increase in the cellular health category.

Riding the same wave, search interest in peptides surged 550%, and 41% of consumers say they’re more aware of peptides than five years ago.

Fresh formats. While 65% of supplement users still prefer pills, 34% say new delivery methods would help them stay consistent. In particular, liquid vitamins sales jumped 50%, while searches for creatine gummies spiked 1,300%.

Trust matters. As the category grows, so does confusion. Doctors (59%), family (40%), and friends (28%) are the most trusted sources. Skeptical, only 11% trust influencers, and 15% cite TikTok as a top discovery channel.

Gaining ground, 35% of consumers use AI for health research, and 27% say they’re open to it. But even as tech plays a bigger role, the desire for credible, human-backed guidance remains strong.

Takeaway: From protein to peptides, consumers want stacks that work. Backed by science, built for real life, and grounded in trust, the next era of wellness is about results.

Fitt Insider
Fitt Insider
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